1- Azad University
2- Science and Arts university
2- Science and Arts university
Abstract: (201 Views)
Background & Objective: Premenstrual syndrome (PMS) is defined as a set of recurrent physical, cognitive, emotional and behavioral symptoms affecting women, which occur cyclically during the luteal phase of the menstrual cycle and in Or it resolves within a few days after the onset of menstruation. It is one of the types of mood disorders that occurs simultaneously with the menstrual cycle of women and is accompanied by physical, mental and emotional symptoms. Premenstrual syndrome is defined as a cluster of recurrent physical, cognitive, emotional, and behavioral symptoms affecting women that occur cyclically during the luteal phase of the menstrual cycle and occur on or over several days. It resolves after the onset of menstruation. Wu et al. reported that emotion dysregulation is considered as a vulnerability factor for mood disorders. However, little information is available on the effect of emotion regulation on women with PMS. Few studies to date have evaluated the relationship between PMS and emotion regulation. A meta-analysis showed that 61.7% of studies reported a significant correlation between the menstrual cycle and emotion regulation. So far, many pharmaceutical and non-pharmacological treatments have been used for PMS. Transcranial Direct Current Stimulation of the brain is a non-invasive technique that uses a constant but weak direct current sent through at least two electrodes, anodic and cathodic, on the scalp, and is able to stimulate neural networks in the brain to increase or decrease. Modulate excitability and neuroplasticity. There is very little research on the effect of tDCS on emotion regulation, however, so far no study has investigated the effect of tDCS on premenstrual boredom syndrome and its psychological symptoms. Women with premenstrual boredom syndrome endure many psychological problems, and emotion regulation plays a very key role in the treatment of other psychological problems of this syndrome, such as anger and arousal. Also, so far, no study has investigated the effectiveness of transcranial Direct Current Stimulation of the left anodic/right cathodic brain in the DLPFC region in regulating the emotions of patients with premenstrual boredom syndrome. Therefore, the aim of this study was to determine the effectiveness of transcranial Direct Current Stimulation of the brain in regulating the emotions of patients with premenstrual syndrome.
Methods: In this semi-experimental study with pre-test and post-test, among the women suffering from premenstrual boredom syndrome in Yazd city, 30 eligible volunteers in the age range of 30 to 40 years entered the study in a simple random manner. 15 of them were randomly assigned to the intervention group and 15 to the control group. Emotion regulation variable scores were compared by Gratz and Romer (2004) emotion regulation questionnaire at two time points before and after electrical stimulation treatment. Data analysis was done using covariance analysis. The significance level of the tests was 0.05.
Results: Data analysis showed that the score of emotion regulation test in women with premenstrual boredom syndrome in the intervention group and after receiving the treatment decreased significantly compared to the control group respectively (P=0.001).
Conclusion: To explain the results of this research, it can be said that patients with premenstrual boredom syndrome and are treated with 10 sessions of 20 minutes of 2 mA of left anodic/right cathodic stimulation of the DLPFC region, anodic tDCS increases the excitability of the underlying cortex. , while cathodal tDCS reduces the excitability of the underlying cortex. In addition to short-term effects, tDCS can induce long-term changes at the synaptic level through mechanisms similar to long-term potentiation, leading to increased neuronal plasticity. Based on several pharmacological studies, calcium-dependent synaptic plasticity of glutamatergic neurons is thought to underlie the neuroplastic mechanism of tDCS effect, as blockade of N-methyldiaspartate receptors reduces the effects of tDCS. In addition to excitatory activity, tDCS can also locally reduce gamma-aminobutyric acid (GABA) neurotransmission. These neuroplasticity changes caused by anodic tDCS in the left DLPFC area (inhibition of the right DLPFC through cathodal tDCS leads to further strengthening of the left DLPFC) with the communication effect that this area has on the amygdala, which is the brain's emotion regulation center, leads to improved regulation. Excitement in women with PMS.
Methods: In this semi-experimental study with pre-test and post-test, among the women suffering from premenstrual boredom syndrome in Yazd city, 30 eligible volunteers in the age range of 30 to 40 years entered the study in a simple random manner. 15 of them were randomly assigned to the intervention group and 15 to the control group. Emotion regulation variable scores were compared by Gratz and Romer (2004) emotion regulation questionnaire at two time points before and after electrical stimulation treatment. Data analysis was done using covariance analysis. The significance level of the tests was 0.05.
Results: Data analysis showed that the score of emotion regulation test in women with premenstrual boredom syndrome in the intervention group and after receiving the treatment decreased significantly compared to the control group respectively (P=0.001).
Conclusion: To explain the results of this research, it can be said that patients with premenstrual boredom syndrome and are treated with 10 sessions of 20 minutes of 2 mA of left anodic/right cathodic stimulation of the DLPFC region, anodic tDCS increases the excitability of the underlying cortex. , while cathodal tDCS reduces the excitability of the underlying cortex. In addition to short-term effects, tDCS can induce long-term changes at the synaptic level through mechanisms similar to long-term potentiation, leading to increased neuronal plasticity. Based on several pharmacological studies, calcium-dependent synaptic plasticity of glutamatergic neurons is thought to underlie the neuroplastic mechanism of tDCS effect, as blockade of N-methyldiaspartate receptors reduces the effects of tDCS. In addition to excitatory activity, tDCS can also locally reduce gamma-aminobutyric acid (GABA) neurotransmission. These neuroplasticity changes caused by anodic tDCS in the left DLPFC area (inhibition of the right DLPFC through cathodal tDCS leads to further strengthening of the left DLPFC) with the communication effect that this area has on the amygdala, which is the brain's emotion regulation center, leads to improved regulation. Excitement in women with PMS.
Type of Study: Original Research Article |
Subject:
Rehabilitation
Send email to the article author
| Rights and permissions | |
 |
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
