Ethics code: IR.IAU.K.REC.1403.200
Abstract: (8 Views)
Background and Objectives: Identifying appropriate treatment programs for improving symptoms of bipolar I disorder plays an important role in preventing disease relapse. This research was conducted with the aim of comparing the effectiveness of pharmacotherapy with combined treatment of emotion regulation cognitive group therapy plus medication on manic symptoms, depression, and suicidal thoughts in patients diagnosed with bipolar I disorder.
Methods: The research method was quasi-experimental with a pretest-posttest-follow-up design. The statistical population included all patients diagnosed with bipolar disorder at Payambaran Hospital in Tehran in 2023. Thirty eligible volunteers entered the study and were randomly assigned to pharmacotherapy (15 people) and combined treatment (15 people) groups. Data collection was performed using structured diagnostic interviews, Young's Mania Rating Scale (1987), Beck's Depression Inventory (1961), and Beck's Suicide Scale (1961). Data were analyzed using SPSS.v26 software with repeated measures ANOVA and Bonferroni post hoc test.
Findings: The within-group time effect was significant for manic symptoms (P<0.001), death wish (P<0.001), suicidal preparedness (P<0.001), active suicidal ideation (P=0.011) and total suicide score (P<0.001). The group effect was significant for manic symptoms (P<0.001), depressive symptoms (P<0.001) and suicidal thoughts (P=0.026), indicating there were significant differences between the two interventions regarding these variables. For all variables, combined treatment was more effective than pharmacotherapy (P<0.05).
Conclusion: It is recommended to design structured treatment programs that consider the combination of pharmacotherapy and emotion regulation cognitive group therapy as the primary approach for patients with bipolar I disorder.
Methods: The research method was quasi-experimental with a pretest-posttest-follow-up design. The statistical population included all patients diagnosed with bipolar disorder at Payambaran Hospital in Tehran in 2023. Thirty eligible volunteers entered the study and were randomly assigned to pharmacotherapy (15 people) and combined treatment (15 people) groups. Data collection was performed using structured diagnostic interviews, Young's Mania Rating Scale (1987), Beck's Depression Inventory (1961), and Beck's Suicide Scale (1961). Data were analyzed using SPSS.v26 software with repeated measures ANOVA and Bonferroni post hoc test.
Findings: The within-group time effect was significant for manic symptoms (P<0.001), death wish (P<0.001), suicidal preparedness (P<0.001), active suicidal ideation (P=0.011) and total suicide score (P<0.001). The group effect was significant for manic symptoms (P<0.001), depressive symptoms (P<0.001) and suicidal thoughts (P=0.026), indicating there were significant differences between the two interventions regarding these variables. For all variables, combined treatment was more effective than pharmacotherapy (P<0.05).
Conclusion: It is recommended to design structured treatment programs that consider the combination of pharmacotherapy and emotion regulation cognitive group therapy as the primary approach for patients with bipolar I disorder.
Keywords: Pharmacotherapy, cognitive emotional regulation, mania, depression, suicide, bipolar I disorder
Type of Study: Original Research Article |
Subject:
Psychology
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