Ethics code: IR.ACECR. JDM.REC. 1402.018
Abstract: (33 Views)
Background & Objective: Paranoid personality disorder is a serious and difficult to treat mental disorder that has always been clinically neglected and people suffering from it experience deep and unjustified mistrust towards others. This study was conducted with the aim of determining the effectiveness of transcranial direct electrical stimulation on rumination and anxiety in patients with paranoid personality disorder. Since neural variability is a pathologically important component of many neurological and psychiatric diseases, non-invasive brain stimulation is a potential therapeutic option because it can modulate neural activity. Transcranial direct currect stimulation is a non-invasive technique that stimulates parts of the brain for therapeutic effects and has been introduced as a promising method to increase neural flexibility. It is relatively safe and fast, and compared to other techniques, it can It is more portable, affordable and tolerable. The effect and direction of transcranial direct stimulation effects are influenced by the intensity of stimulation and can increase with repeated stimulation (i.e. cumulative effects). Anodic stimulation of the left prefrontal cortex and inhibition of the right prefrontal cortex are the most promising approaches for anxiety disorders. In connection with chronic, complex and treatment-resistant disorders, focusing on rumination can increase the effectiveness of psychological treatments and improve treatment outcomes. Also, rumination moderates the relationship between anxiety, negative affect and paranoia. Anxiety-related processes contribute to paranoid ideation by directly providing content for paranoid beliefs.
Methods: The current research was a type of experimental study with a pre-test-post-test-follow-up design and a control group. The statistical population of the research included all patients with paranoid personality disorder aged 30 to 45 in Yazd city who referred to psychological and psychiatric clinics and hospitals in Yazd city in 1401. . The sample of this research was considered to be 30 people who voluntarily entered the study by non-random sampling and were randomly placed in two experimental (15 people) and control (15 people) groups. In a pre-test and two-month post-test phase, the participants gave answers to the questionnaires that showed the measurement tool: Hoeksma and Maro's 22-question rumination questionnaire (Hoeksma and Maro, 1991) with an alpha coefficient of 0.90 and retest reliability of 0.67, as well as Beck's 21-question anxiety scale (Beck et al., 1990) with a one-week retest reliability coefficient E 0.75 and internal consistency 0.93. Then, the subjects of the experimental group, during 10 sessions of 20 minutes, on 10 consecutive days, received therapeutic intervention by direct transcranial electrical stimulation of the brain in the dorso-lateral prefrontal cortex. The intervention was carried out in the form of simultaneous anodic stimulation of the left area and cathodic area of the right area of the dorsolateral prefrontal cortex with an intensity of 2 mA. Data analysis using the statistical test of analysis of variance with repeated measurements and Bonferroni's post hoc test in the significance level was 0.05 and it was done with SPSS-27 software.
Results: The results showed that direct transcranial electrical stimulation improved rumination (p<0.001) and anxiety (p<0.001). It resulted in the post-test phase. Also, the scores of rumination and anxiety between the post-test and follow-up stages did not show any significant difference, which indicated the durability of the treatment effects in the follow-up stage.
Conclusion: According to the results of the research, the implementation of direct transcranial electrical stimulation treatment for patients can have beneficial effects in reducing problems related to emotion and cognition in them.
Keyword: Paranoid Personality Disorder, Rumination, Anxiety, Direct Transcranial Electrical Stimulation
Methods: The current research was a type of experimental study with a pre-test-post-test-follow-up design and a control group. The statistical population of the research included all patients with paranoid personality disorder aged 30 to 45 in Yazd city who referred to psychological and psychiatric clinics and hospitals in Yazd city in 1401. . The sample of this research was considered to be 30 people who voluntarily entered the study by non-random sampling and were randomly placed in two experimental (15 people) and control (15 people) groups. In a pre-test and two-month post-test phase, the participants gave answers to the questionnaires that showed the measurement tool: Hoeksma and Maro's 22-question rumination questionnaire (Hoeksma and Maro, 1991) with an alpha coefficient of 0.90 and retest reliability of 0.67, as well as Beck's 21-question anxiety scale (Beck et al., 1990) with a one-week retest reliability coefficient E 0.75 and internal consistency 0.93. Then, the subjects of the experimental group, during 10 sessions of 20 minutes, on 10 consecutive days, received therapeutic intervention by direct transcranial electrical stimulation of the brain in the dorso-lateral prefrontal cortex. The intervention was carried out in the form of simultaneous anodic stimulation of the left area and cathodic area of the right area of the dorsolateral prefrontal cortex with an intensity of 2 mA. Data analysis using the statistical test of analysis of variance with repeated measurements and Bonferroni's post hoc test in the significance level was 0.05 and it was done with SPSS-27 software.
Results: The results showed that direct transcranial electrical stimulation improved rumination (p<0.001) and anxiety (p<0.001). It resulted in the post-test phase. Also, the scores of rumination and anxiety between the post-test and follow-up stages did not show any significant difference, which indicated the durability of the treatment effects in the follow-up stage.
Conclusion: According to the results of the research, the implementation of direct transcranial electrical stimulation treatment for patients can have beneficial effects in reducing problems related to emotion and cognition in them.
Keyword: Paranoid Personality Disorder, Rumination, Anxiety, Direct Transcranial Electrical Stimulation
Keywords: Paranoid Personality Disorder, Rumination, Anxiety, Direct Transcranial Electrical Stimulation
Type of Study: Original Research Article |
Subject:
Psychology
Send email to the article author
| Rights and permissions | |
 |
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
